Biomarker discovery in tropical disease

Challenge

A customer was interested in performing a biomarker discovery study for a number of tropical diseases. They decided to have a large custom peptide array developed and then run patient vs control samples to determine which epitopes on which proteins could be used to develop diagnostic assays.

Solution

BISC Global has helped design the peptide array based on the existing proteomes for Dengue, Yellow Fever, etc. Once the peptide array studies were finished, BISC Global built a custom analysis pipeline and helped the customer with their analysis and determine possible relevant biomarkers.

Impact

With BISC Global’s help, the customer was able to design, run and analyze their experiment resulting in an optimized panel of biomarkers for several tropical diseases. The customer is planning to continue further validating the biomarkers and develop diagnostic assays.

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