Re-analysing database for novel targets

KEYWORDS: siRNA | Statistics & modeling


A customer was interested in finding new potential targets for siRNAs based on their existing databases.


BISC Global performed a study combining following analyses:

  • siRNA hit calling and determining on/off targets
  • Selection of siRNA’s for subsequent toxicity screen
  • Define thresholds for cell viability, toxicity, household gene stability


BISC Global identified compelling on/off-target interactions with limited effects on cell viability and toxicity.

Check our other Resources:

Contact us to discuss your project

    I agree to the privacy policy